6 Patterns > Cellular Infiltrates > Subpatterns

Cellular Infiltrates Sub-Patterns

There are 7 sub-patterns in the setting of cellular infiltrates.

Choose the image most similar to your case.  A differential diagnosis is given below.

SEE BELOW FOR SAMPLE SIGNOUT 

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w/ Lymphocytes and Plasma Cells

  • Subacute HP

  • CTD

  • LIP

  • Cellular NSIP

  • Drug Reaction

  • Lymphoproliferative Disease

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w/ Neutrophils

  • Infection

  • CTD

  • Alveolar Hemorrhage

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w/ Granulomas

  • Subacute HP

  • Sarcoidosis

  • Berylliosis

  • Chronic infection

  • Chronic aspiration

  • Drug Reaction

  • Lymphoma

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w/ Focal Organizing Pneumonia

  • Infection

  • CTD

  • Drug Reaction

  • Idiopathic (COP)

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w/ Fibrin or Hyaline Membranes

  • Acute on Subacute

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w/ Pleuritis and/or lymphoid hyperplasia 

  • CTD

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w/ Fibrosis

  • Subacute on Chronic ILD

Sample Signout of the Cellular Infiltrates Pattern

If no additional specific histologic features are identified, consider the following approach to signing the case out:

Cellular interstitial pneumonia (see comment).

Comment:  The biopsy shows extensive cellular interstitial infiltrates.  No additional specific histologic features to indicate an etiology are identified.  There is a broad differential diagnosis including subacute HP, cellular NSIP, CTD, infection, alveolar hemorrhage, drug reaction, aspiration, lymphoproliferative disease (including LIP), and as an idopathic entity.  The diagnosis of ILD requires a multidisciplinary approach.  Correlation with imaging studies, serology, microbiology studies, and clinical history is suggested.