6 Patterns > Minimal Change > Subpatterns

Minimal Changes Sub-Patterns

There are 4 sub-patterns in the setting of nodules.

Choose the image most similar to your case.  A differential diagnosis is given below.

SEE BELOW FOR SAMPLE SIGNOUT 

min chnage.jpg

w/ Small Airways Disease

  • Constrictive bronchiolitis

cyst.jpg

w/ Cysts

  • Lymphangioleiomyomatosis

  • PLCH

  • Brit-Hoag Dube

  • Lymphoid interstitial pneumonia

pvod copy.jpg

w/ Vascular Disease

  • Pulmonary Hypertension

  • Veno-occlusive disease

normal.jpg

w/ No Specific Findings

  • Early acute lung injury

  • Pulmonary edema

  • Sampling error

Sample Signout of the Minimal Changes Pattern

If no additional specific histologic features are identified, consider the following approach to signing the case out:

Generous biopsy showing minimal pathologic changes (see comment).

Comment:  The biopsy shows minimal pathologic changes. This is seen most commonly in the setting of small airways disease and the clinical syndrome of constrictive bronchiolitis. The differential diagnosis also includes vascular abnormalities, cystic lung disease, and sampling error. Correlation with imaging studies, serology, microbiology studies, and clinical history is suggested.