6 Patterns > Acute Lung Injury Pattern > Subpatterns > w/ Cellular Interstitial Infiltrates

Acute Lung Injury w/ Cellular Interstitial Infiltrates

Click the image your case is most similar to:

Infection

Drug Reaction

Connective Tissue Dissease

Foreign Material (vascular or inhalational)

Idiopathic DAD/ARDS

Sample Signout

If no additional specific histologic features are identified, consider the following approach to signing the case out:

Acute and organizing diffuse alveolar damage with hyaline membranes (see comment).

Comment:  The biopsy shows extensive acute lung injury in the form of hyaline membranes, edema, and areas of organization.  This is a nonspecific pattern seen a variety of settings including infection, connective tissues disease, adverse drug reaction, and as an idiopathic entity.  Histologic clues to a specific etiology are not identified.  No significant background fibrosis to suggest a chronic interstitial lung disease is appreciated.  Correlation with final culture studies is suggested to completely exclude infection although there is no necrosis, viral cytopathic effect, granulomas, or extensive neutrophils.  Should no definitive etiology be identified, this may represent idiopathic DAD/ARDS.