6 Patterns > Fibrosis Pattern > Additional Features > w/ Diffuse Alveolar Wall Fibrosis
Fibrosis w/ Diffuse Alveolar Wall Fibrosis
Click the image your case is most similar to:
CTD-associated ILD
Idiopathic Fibrotic Nonspecific Interstitial Pneumonia
Other considerations:
Adverse Drug Reaction
Healing/Healed Acute lung injury
Pneumoconioses
Immunodeficiency Syndromes (CVID)
Chronic Hypersensitivity Pneumonitis
Smoking Related Interstitial Fibrosis (SRIF)
Sample SIgnout
If no additional specific histologic features are identified, consider the following approach to signing the case out:
Fibrotic nonspecific interstitial pneumonia pattern of pulmonary fibrosis (see comment).
Comment: The biopsy shows a diffuse fibrosing process affecting nearly all alveolar walls, most consistent with a fibrotic NSIP pattern of pulmonary fibrosis. No additional specific histologic features to indicate an etiology are identified. There is a broad differential diagnosis including CTD-associated ILD, chronic HP, adverse drug reaction, and pneumoconiosis among others. If no etiology is identified clinically, this biopsy would meet criteria for the idiopathic disease, fibrotic nonspecific interstitial pneumonia. The diagnosis of ILD requires a multidisciplinary approach. Correlation with imaging studies and clinical history is suggested.